Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14987029 | 0.94 | GLS (1.00) | GLS | |
| SCHEMBL15042399 | 0.88 | GLS (0.87) | GLS | |
| SCHEMBL21443341 | 0.88 | GLS (0.91) | GLS | |
| SCHEMBL21466363 | 0.87 | GLS (0.85) | GLS | |
| SCHEMBL21443376 | 0.86 | GLS (0.88) | GLS | |
| SCHEMBL14977268 | 0.86 | GLS (1.00) | GLS | |
| SCHEMBL21443421 | 0.86 | GLS (0.68) | GLS | |
| SCHEMBL14987486 | 0.85 | GLS (1.00) | GLS | |
| SCHEMBL14977152 | 0.85 | GLS (0.82) | GLS | |
| SCHEMBL14977150 | 0.85 | GLS (0.82) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782570-B1 | HETEROCYCLIC INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES INC (US) | 2019-09-18 | — | — | EP | disclosed |