SCHEMBL21369977

SCHEMBL21369977

COC(=O)Oc1ccc(COc2ccc(OC)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.64
POLB P06746 1/20 0.64
RAB9A P51151 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
ALDH1A1 P00352 1/20 0.63
MAPT P10636 1/20 0.63
HTT P42858 1/20 0.63
APP P05067 5/20 0.62
FFAR1 O14842 8/20 0.60
PLA2G4B P0C869 1/20 0.56
MAOB P27338 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21991256 0.87 MAOB (0.63) NPC1RAB9AAPPFFAR1MAOB
SCHEMBL14408671 0.84 SAE1 (0.62) SMN1; SMN2ALDH1A1HTT
SCHEMBL697317 0.84 CA1 (0.56) NPC1RAB9ASMN1; SMN2ALDH1A1HTT
SCHEMBL21991493 0.83 MAOB (0.66) FFAR1MAOB
SCHEMBL20000873 0.82 APP (0.80) NPC1POLBRAB9ASMN1; SMN2ALDH1A1
SCHEMBL2636206 0.80 HTT (0.49) NPC1POLBRAB9ASMN1; SMN2ALDH1A1
SCHEMBL19926288 0.80 ALDH1A1 (0.65) NPC1POLBRAB9ASMN1; SMN2ALDH1A1
SCHEMBL3729907 0.80 NPC1 (0.75) NPC1POLBRAB9ASMN1; SMN2ALDH1A1
SCHEMBL697621 0.79 ALDH1A1 (0.61) NPC1POLBRAB9ASMN1; SMN2ALDH1A1
SCHEMBL18821722 0.78 SMN1; SMN2 (0.66) NPC1POLBRAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019176717-A1 CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE USING SAME 住友化学株式会社 2019-09-19 WO disclosed