Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 18/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21370042 | 0.90 | OGA (0.37) | OGALMNAOPRK1 | |
| SCHEMBL21369594 | 0.90 | OGA (0.37) | OGALMNAOPRK1 | |
| SCHEMBL21370278 | 0.87 | OGA (0.53) | OGAOPRK1 | |
| SCHEMBL22964756 | 0.87 | OGA (0.53) | OGAOPRK1 | |
| SCHEMBL21359550 | 0.87 | OGA (0.53) | OGAOPRK1 | |
| SCHEMBL21359528 | 0.87 | OGA (0.53) | OGAOPRK1 | |
| SCHEMBL21370039 | 0.87 | OGA (0.53) | OGAOPRK1 | |
| SCHEMBL21370047 | 0.86 | OGA (0.33) | OGALMNA | |
| SCHEMBL22078755 | 0.84 | LMNA (0.37) | OGALMNAGAAOPRK1 | |
| SCHEMBL21369622 | 0.83 | OGA (0.35) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |