Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21370626 | 0.88 | KMT2A (0.52) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370554 | 0.85 | KMT2A (0.50) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370549 | 0.85 | CYP1A1 (0.52) | TTRMAPTLMNAKDM4EMEN1 | |
| Triacetylresveratrol SCHEMBL717980 | 0.83 | TTR (1.00) | TTRMAPTLMNAKDM4EMEN1 | |
| Triacetylresveratrol SCHEMBL717979 | 0.83 | TTR (1.00) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370600 | 0.82 | KMT2A (0.48) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370602 | 0.81 | KMT2A (0.47) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370601 | 0.81 | KMT2A (0.47) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL21370547 | 0.81 | CYP1A1 (0.60) | TTRMAPTLMNAKDM4EMEN1 | |
| SCHEMBL18428448 | 0.81 | TTR (0.70) | TTRMAPTLMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284213-A1 | SILYLATED DERIVATIVES OF RESERVATROL AND THE USE THEREOF IN NEURODEGENERATIVE, NEUROLOGICAL OR INFLAMMATORY DISEASES | SIRT1, SIRT3, SIRT2 | TTR 2737/4885MAPT 103/4885LMNA 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.