Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139329 | 0.92 | AKR1B1 (0.54) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL4367663 | 0.90 | AKR1B1 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL2201929 | 0.89 | TSHR (0.46) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL30219827 | 0.87 | TSHR (0.46) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9175772 | 0.87 | TSHR (0.44) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9179888 | 0.87 | TSHR (0.44) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9178193 | 0.87 | TSHR (0.44) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL11307948 | 0.87 | TSHR (0.55) | AKR1B1GPR84TSHRALDH1A1KMT2A | |
| SCHEMBL9179933 | 0.85 | TDP1 (0.43) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL11596995 | 0.85 | TSHR (0.42) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7862749-B2 | Flame retardant polyurethanes and additives therefor | ALBEMARLE CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| EP-2107079-A2 | Flame retardants with high halogen content and low viscosity | Albermarle Corporation (US) | 2009-10-07 | — | — | EP | disclosed |
| EP-1664179-B1 | FLAME RETARDANTS WITH HIGH HALOGEN CONTENT AND LOW VISCOSITY | ALBEMARLE CORP (US) | 2009-07-15 | — | — | EP | disclosed |
| US-7381354-B2 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION (US) | 2008-06-03 | — | — | US | disclosed |
| US-20070276055-A1 | Flame Retardant Polyurethanes and Additives Therefor | ALBEMARLE CORPORATION (US) | 2007-11-29 | — | — | US | disclosed |
| EP-1756224-B1 | FLAME RETARDANT POLYURETHANES AND ADDITIVES THEREFOR | ALBEMARLE CORP (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20070225517-A1 | Flame Retardants With High Halogen Content and Low Viscosity | ALBEMARLE CORPORATION (US) | 2007-09-27 | — | — | US | disclosed |
| US-7258823-B2 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1756224-A1 | FLAME RETARDANT POLYURETHANES AND ADDITIVES THEREFOR | ALBEMARLE CORPORATION (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1664179-A1 | FLAME RETARDANTS WITH HIGH HALOGEN CONTENT AND LOW VISCOSITY | ALBEMARLE CORPORATION (US) | 2006-06-07 | — | — | EP | disclosed |
| US-7045564-B2 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION (US) | 2006-05-16 | — | — | US | disclosed |
| WO-2005118720-A1 | FLAME RETARDANT POLYURETHANES AND ADDITIVES THEREFOR | ALBEMARLE CORPORATION (US) | 2005-12-15 | — | — | WO | disclosed |
| WO-2005023927-A1 | FLAME RETARDANTS WITH HIGH HALOGEN CONTENT AND LOW VISCOSITY | ALBEMARLE CORPORATION (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050045857-A1 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION | 2005-03-03 | — | — | US | disclosed |
| US-20050045858-A1 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION | 2005-03-03 | — | — | US | disclosed |