Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30219827 | 0.91 | TSHR (0.46) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL28605806 | 0.89 | TSHR (0.44) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL27539128 | 0.87 | HIF1A (0.68) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL2141703 | 0.87 | ALDH1A1 (0.54) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL2137158 | 0.87 | AKR1B1 (0.48) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| Rubidium SCHEMBL11438713 | 0.85 | ALDH1A1 (0.52) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL11438710 | 0.85 | ALDH1A1 (0.52) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL9240889 | 0.83 | NAALAD2 (0.46) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 | |
| SCHEMBL11309130 | 0.82 | LMNA (0.52) | TSHRHIF1ACYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL11514765 | 0.81 | NAALAD2 (0.45) | TSHRHIF1ACYP2D6CYP2C19NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257958-A | INORGANIC BORON-OXYGEN COMPOUND ADDITIVES | TEXACO INC. (US) | 1981-03-24 | — | — | US | disclosed |