Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546878 | 0.74 | DYRK1A (0.48) | TDO2PTPN11 | |
| SCHEMBL18500595 | 0.65 | PTPN11 (0.54) | TDO2PTPN11 | |
| SCHEMBL17383748 | 0.65 | IDO1 (0.36) | — | |
| SCHEMBL3324842 | 0.65 | PDGFRB (0.51) | TDO2 | |
| SCHEMBL14828956 | 0.64 | — | — | |
| SCHEMBL5437662 | 0.64 | — | — | |
| SCHEMBL29895057 | 0.63 | PTPN11 (0.44) | TDO2PTPN11 | |
| SCHEMBL19001482 | 0.59 | CYP1A2 (0.43) | — | |
| SCHEMBL18848507 | 0.58 | ESR2 (0.41) | — | |
| SCHEMBL360056 | 0.57 | KMT2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3639824-A1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-04-22 | — | — | EP | disclosed |
| EP-3182973-B1 | TRICYCLIC NITROGEN CONTAINING COMPOUNDS FOR TREATING NEISSERIA GONORRHOEA INFECTION | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-09-18 | — | — | EP | disclosed |