SCHEMBL360056

SCHEMBL360056

Clc1nc2cc(I)cnc2s1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19341416 0.80 KMT2A (0.34) KMT2AIDO1
SCHEMBL368876 0.77 KMT2A (0.33) KMT2A
SCHEMBL359702 0.77 SMN1; SMN2 (0.36) IDO1
SCHEMBL24869554 0.73 HDAC6 (0.34) KMT2A
SCHEMBL12724429 0.73
SCHEMBL25425637 0.72 MGAM (0.44) KMT2A
SCHEMBL31456669 0.69 KMT2A (0.34) KMT2A
SCHEMBL12702002 0.69 ACACB (0.34)
SCHEMBL17926571 0.68 EGFR (0.33) KMT2A
SCHEMBL31456653 0.67 SMN1; SMN2 (0.43) KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012007510-A1 COMPOUNDS FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-01-19 WO disclosed