SCHEMBL2137239

SCHEMBL2137239

C=CC(CC=CC)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 4/20 0.38
GRIK2 Q13002 4/20 0.38
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
BLM P54132 1/20 0.35
SLC6A3 Q01959 1/20 0.35
MEN1 O00255 1/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC2 Q92769 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
CTSK P43235 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27871355 1.00 GRIK1 (0.38) GRIK1GRIK2SLC6A2SLC6A4BLM
SCHEMBL11136259 0.80 CYP2D6 (0.48) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL4280331 0.78 SLC22A6 (0.43) SLC6A2SLC6A4BLMSLC6A3MEN1
SCHEMBL614027 0.74
SCHEMBL7702223 0.72 SLC6A2 (0.54) GRIK1GRIK2SLC6A2SLC6A4BLM
SCHEMBL6329381 0.72 SLC22A6 (0.52) GRIK1GRIK2NFKB1HDAC2SLC22A6
SCHEMBL21986677 0.72 GRIK1 (0.41) GRIK1GRIK2HDAC2SLC22A6CTSK
SCHEMBL6329384 0.72 SLC22A6 (0.52) GRIK1GRIK2NFKB1HDAC2SLC22A6
SCHEMBL14915014 0.72
SCHEMBL28518615 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684341-A Double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2025-03-25 CN disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-111433235-B Capped double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
US-11359038-B2 Capped multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
CN-111448200-A Dual head organoaluminum compositions 陶氏环球技术有限责任公司 2020-07-24 CN disclosed
CN-111433235-A Capped dual head organoaluminum compositions 陶氏环球技术有限责任公司 2020-07-17 CN disclosed
EP-3519474-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2019-08-07 EP disclosed
EP-3519456-A1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-07 EP disclosed
WO-2018064546-A1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
WO-2018064540-A1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-05 WO disclosed
EP-2450361-B1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF MITSUI CHEMICALS INC (JP) 2017-10-25 EP disclosed
US-8791284-B2 Organometallic compound and production method thereof MITSUI CHEMICALS, INC. (JP) 2014-07-29 US disclosed
EP-2450361-A1 ORGANOMETALLIC COMPOUNDS AND PROCESS FOR PREPARATION THEREOF Mitsui Chemicals, Inc. (JP) 2012-05-09 EP disclosed
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS, INC. 2012-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 GRIK1 4282/4885GRIK2 3829/4885SLC6A2 4321/4885
US-20120101289-A1 ORGANOMETALLIC COMPOUND AND PRODUCTION METHOD THEREOF SLC39A11, AP2M1, AP1M1 GRIK1 107/4885GRIK2 398/4885SLC6A2 4669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.