Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619647 | 1.00 | — | — | |
| SCHEMBL10607054 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL10605594 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL9422095 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL10603687 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL8592680 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL10605582 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL4349948 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL10607099 | 1.00 | TSHR (0.47) | TSHRTHRBALDH1A1CES2CES1 | |
| SCHEMBL22283422 | 0.81 | TSHR (0.53) | TSHRTHRBALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954343-B2 | Compositions comprising beta-ketocarbonyl-functional organosilicon compounds | WACKER CHEMIE AG (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20190345292-A1 | COMPOSITIONS COMPRISING BETA-KETOCARBONYL-FUNCTIONAL ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2019-11-14 | — | — | US | disclosed |
| EP-3541986-A1 | COMPOSITIONS CONTAINING BETA-KETOCARBONYL-FUNCTIONAL ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2019-09-25 | — | — | EP | disclosed |