SCHEMBL4349948

SCHEMBL4349948

CCCCCCCC[SiH](C)[O]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 2/20 0.43
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
EPHX2 P34913 1/20 0.38
DNM1 Q05193 5/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10619647 1.00
SCHEMBL10607054 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL10605594 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL9422095 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL10603687 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL8592680 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL10605582 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL10607099 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL21372501 1.00 TSHR (0.47) TSHRTHRBALDH1A1CES2CES1
SCHEMBL22283422 0.81 TSHR (0.53) TSHRTHRBALDH1A1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024017471-A1 DEFOAMING COMPOSITIONS FOR DETERGENTS WACKER CHEMIE AG (DE) 2024-01-25 WO disclosed
CN-110267730-B Modified siloxane composite membrane for heavy hydrocarbon recovery 沙特阿拉伯石油公司 2022-02-01 CN disclosed
US-10293301-B2 Modified siloxane composite membranes for heavy hydrocarbon recovery SAUDI ARABIAN OIL COMPANY (SA) 2019-05-21 US disclosed
US-10253168-B2 Additive composition for amine hardeners, use of said additive composition, and amine hardener composition containing said additive composition HILTI AKTIENGESELLSCHAFT (LI) 2019-04-09 US disclosed
US-20180221813-A1 MODIFIED SILOXANE COMPOSITE MEMBRANES FOR HEAVY HYDROCARBON RECOVERY SAUDI ARABIAN OIL COMPANY (SA) 2018-08-09 US disclosed
US-9968866-B2 Process for defoaming aqueous compositions containing surfactants WACKER CHEMIE AG (DE) 2018-05-15 US disclosed
EP-3007793-B1 PROCESS FOR DEFOAMING AQUEOUS COMPOSITIONS CONTAINING SURFACTANTS, AND DEFOAMING FORMULATIONS WACKER CHEMIE AG (DE) 2017-04-26 EP disclosed
US-20160121239-A1 PROCESS FOR DEFOAMING AQUEOUS COMPOSITIONS CONTAINING SURFACTANTS WACKER CHEMIE AG (DE) 2016-05-05 US disclosed
US-20160075861-A1 Additive Composition for Amine Hardeners, Use of Said Additive Composition, and Amine Hardener Composition Containing Said Additive Composition HILTI AKTIENGESELLSCHAFT (LI) 2016-03-17 US disclosed
EP-2978722-A1 ADDITIVE COMPOSITION FOR AMINE HARDENERS, USE OF SAID ADDITIVE COMPOSITION, AND AMINE HARDENER COMPOSITION CONTAINING SAID ADDITIVE COMPOSITION Hilti Aktiengesellschaft (LI) 2016-02-03 EP disclosed
WO-2014154675-A1 ADDITIVE COMPOSITION FOR AMINE HARDENERS, USE OF SAID ADDITIVE COMPOSITION, AND AMINE HARDENER COMPOSITION CONTAINING SAID ADDITIVE COMPOSITION HILTI AKTIENGESELLSCHAFT (LI) 2014-10-02 WO disclosed
US-7566750-B2 Defoamer compositions WACKER CHEMIE AG (DE) 2009-07-28 US disclosed
US-20060160908-A1 Defoamer compositions WACKER CHEMIE AG (DE) 2006-07-20 US disclosed
EP-0329279-B1 Silicone release compositions MINNESOTA MINING & MFG (US) 1993-10-20 EP disclosed
EP-0329279-A2 Silicone release compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-23 EP disclosed
US-4822687-A EPOXYPOLYSILOXANE COMPOSITE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-04-18 US disclosed
US-4275133-A Electrophotographic imaging processes utilizing adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1981-06-23 US disclosed
US-4181772-A Adhesive generator overcoated photoreceptors XEROX CORPORATION (US) 1980-01-01 US disclosed