Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21372682 | 0.88 | IDO1 (0.52) | IDO1 | |
| SCHEMBL21372781 | 0.86 | IDO1 (0.42) | IDO1 | |
| SCHEMBL21372927 | 0.86 | IDO1 (0.47) | IDO1 | |
| SCHEMBL21373045 | 0.86 | IDO1 (0.42) | IDO1 | |
| SCHEMBL21373039 | 0.85 | IDO1 (0.41) | IDO1 | |
| SCHEMBL21372968 | 0.85 | IDO1 (0.41) | IDO1 | |
| SCHEMBL21373044 | 0.84 | MKNK1 (0.39) | IDO1 | |
| SCHEMBL21373108 | 0.84 | IDO1 (0.40) | IDO1 | |
| SCHEMBL21372633 | 0.84 | IDO1 (0.41) | IDO1 | |
| SCHEMBL21372855 | 0.83 | CYP3A4 (0.44) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3294732-B1 | BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE | GILEAD SCIENCES INC (US) | 2019-09-25 | — | — | EP | claimed |