Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648636 | 1.00 | MAPT (0.40) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL28649268 | 0.94 | MAPT (0.39) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL2138706 | 0.94 | MAPT (0.39) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL1563329 | 0.92 | MAPT (0.41) | MAPTKDM4EKMT2AMETLMNA | |
| SCHEMBL28650586 | 0.92 | MAPT (0.41) | MAPTKDM4EKMT2AMETLMNA | |
| SCHEMBL2136564 | 0.89 | MET (0.38) | MAPTKDM4ENR1H4METLMNA | |
| SCHEMBL28648613 | 0.88 | MAPT (0.39) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL2138812 | 0.88 | MAPT (0.39) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL2138858 | 0.87 | MAPT (0.41) | MAPTKDM4ENR1H4KMT2AMEN1 | |
| SCHEMBL1563980 | 0.85 | MAPT (0.39) | MAPTKDM4EKMT2AMETLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | PARG, PARN, PUF60 | MAPT 159/4885KDM4E 2018/4885NR1H4 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.