⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL219895 | 0.81 | TDP1 (0.61) | — | |
| SCHEMBL30026816 | 0.79 | CYP3A4 (0.86) | — | |
| SCHEMBL1389429 | 0.79 | CYP3A4 (0.86) | — | |
| SCHEMBL30833243 | 0.78 | KMT2A (0.67) | — | |
| SCHEMBL17508206 | 0.78 | KMT2A (0.67) | — | |
| SCHEMBL30833244 | 0.78 | KMT2A (0.67) | — | |
| SCHEMBL31388534 | 0.77 | — | — | |
| SCHEMBL13302358 | 0.77 | CYP3A4 (0.82) | — | |
| SCHEMBL2934239 | 0.77 | — | — | |
| Phenylhydrazine SCHEMBL28961300 | 0.77 | TDP1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343556-A | Bio-based compound modified cracking carbon black and application thereof in tire preparation | 中策橡胶集团股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117247639-A | Tire inner liner rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-117247608-A | Tire pad rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-103570581-A | Synthesis method of 3-hydroxy phenylhydrazine | JIANGSU YINGLI TECHNOLOGY DEV CO LTD | 2014-02-12 | — | — | CN | claimed |
| US-11883500-B2 | Phosphonate linkers and their use to facilitate cellular retention of compounds | MERCK SHARP & DOHME LLC (US) | 2024-01-30 | — | — | US | disclosed |
| CN-117343556-A | Bio-based compound modified cracking carbon black and application thereof in tire preparation | 中策橡胶集团股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-3407916-B1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3407916-B1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-117247639-A | Tire inner liner rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117247608-A | Tire pad rubber composition containing bio-based modified cracking carbon black, mixing method and tire | 中策橡胶集团股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-114805118-B | Perillaldehyde derivative and preparation method and application thereof | 广西大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20230147502-A1 | PHOSPHONATE LINKERS AND THEIR USE TO FACILIATE CELLULAR RETENTION OF COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2023-05-11 | — | — | US | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0105721-B1 | 2-SUBSTITUTED PHENYL-4,5,6,7-TETRAHYDRO-2H-INDAZOLES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-11 | — | — | EP | disclosed |
| EP-0179217-A2 | Process for the preparation of 2-hydroxy-5,6,7,8-tetrahydrocarbazol and its salts, and their uses | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-04-30 | — | — | EP | disclosed |
| US-4226774-A | Carbazole melonates | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4193923-A | Tetrahydro 2-carbazolyl methyl malonate derivatives | HOFFMANN-LA ROCHE INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4158007-A | Carbazole methyl malonates | HOFFMANN-LA ROCHE INC. (US) | 1979-06-12 | — | — | US | disclosed |