SCHEMBL219895

SCHEMBL219895

NNc1cccc(NN)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.61
IDO1 P14902 4/20 0.61
LMNA P02545 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
PTGS2 P35354 1/20 0.61
NOS1 P29475 1/20 0.52
MAPT P10636 4/20 0.48
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
ALDH1A1 P00352 3/20 0.48
AR P10275 1/20 0.48
KDM4E B2RXH2 3/20 0.44
GAA P10253 2/20 0.44
GFER P55789 1/20 0.44
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11485819 0.87 NOS1 (0.48) TDP1IDO1LMNACYP3A4CYP1A2
SCHEMBL2141808 0.85
SCHEMBL31418767 0.81
SCHEMBL28136801 0.81
SCHEMBL25514701 0.81
SCHEMBL3273497 0.81
SCHEMBL7658 0.81
SCHEMBL8318 0.81
SCHEMBL1143757 0.81
SCHEMBL2137363 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4377368-B1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2025-06-18 EP disclosed
US-20240352178-A1 AQUEOUS POLYURETHANE DISPERSION ALLNEX AUSTRIA GMBH (AT) 2024-10-24 US disclosed
EP-4400523-A1 AQUEOUS POLYURETHANE-VINYL POLYMER HYBRID DISPERSION Allnex Austria GmbH (AT) 2024-07-17 EP disclosed
CN-117642443-A Aqueous polyurethane dispersions 湛新奥地利有限公司 2024-03-01 CN disclosed
WO-2022070823-A1 CLEAR COATING COMPOSITION 日本ペイントホールディングス株式会社 2022-04-07 WO disclosed
CN-109021281-B Composite foaming agent and application thereof in preparation of polyurethane foam 广西斯佰祥科技产业有限公司 2021-11-26 CN disclosed
CN-109021280-B Preparation method of polyurethane foam and polyurethane foam 淮北市星光新材料科技有限公司 2021-11-12 CN disclosed
CN-105246690-A Multilayer coating film and method for forming multilayer coating film NIPPON PAINT CO LTDK 2016-01-13 CN disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS CANNIZZARO CARINA 2009-10-01 US disclosed
WO-2004096236-A2 IMMUNOMODULATOR PHOSPHONATE CONJUGATES GILEAD SCIENCES, INC. (US) 2004-11-11 WO disclosed
EP-0341886-B1 Aqueous coating compositions ZENECA RESINS BV (NL) 1994-12-07 EP disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4988762-A Crosslinking coating comprising aziridine-modified addition polymers having pendant ketones or aldehydes; protective coatings; adhesives; imination ICI RESINS B.V. (NL) 1991-01-29 US disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0341886-A2 Aqueous coating compositions ZENECA RESINS BV (NL) 1989-11-15 EP disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed
EP-0003516-B1 AQUOUS DISPERSIONS OF COPOLYMERS WITH CARBONYL GROUPS THAT CONTAIN HYDRAZINE DERIVATIVES AND HEAVY METAL IONS BASF Aktiengesellschaft (DE) 1981-04-01 EP disclosed
US-4250070-A ALSO CONTAINING HEAVY METAL IONS; STORAGE STABILITY; CROSSLINKING; COATINGS BASF AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
EP-0003516-A1 Aquous dispersions of copolymers with carbonyl groups that contain hydrazine derivatives and heavy metal ions BASF Aktiengesellschaft (DE) 1979-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS PHOSPHO1, TNF, PTGES TDP1 3075/4885IDO1 2388/4885LMNA 2591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.