Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.59 |
| ▸ | MME | P08473 | 7/20 | 0.59 |
| ▸ | CPA1 | P15085 | 2/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468859 | 1.00 | ACE (0.59) | ACEMMECPA1ACE2ALDH1A1 | |
| SCHEMBL10588631 | 0.85 | ACE (0.59) | ACEMMECPA1ACE2 | |
| SCHEMBL930679 | 0.80 | ACE (0.57) | ACEMMECPA1ACE2ALDH1A1 | |
| SCHEMBL9730271 | 0.79 | ACE (0.53) | ACEMMECPA1ACE2 | |
| SCHEMBL7725288 | 0.79 | MME (0.52) | ACEMMECPA1ACE2LMNA | |
| SCHEMBL9652457 | 0.79 | MME (0.52) | ACEMMECPA1ACE2LMNA | |
| SCHEMBL7362168 | 0.79 | MME (0.52) | ACEMMECPA1ACE2LMNA | |
| SCHEMBL21000307 | 0.78 | MME (0.52) | ACEMMECPA1ACE2 | |
| SCHEMBL4572623 | 0.77 | MME (0.50) | ACEMMECPA1ACE2LMNA | |
| SCHEMBL6374397 | 0.77 | MME (0.50) | ACEMMECPA1ACE2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174279-A1 | 1,2-BENZISOSELENAZOL-3(2H)-ONE AND 1,2-BENZISOTHIAZOL-3(2H)-ONE DERIVATIVES AS BETA-LACTAM ANTIBIOTIC ADJUVANTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2019-09-19 | — | — | WO | disclosed |