Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.53 |
| ▸ | MME | P08473 | 7/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588631 | 0.79 | ACE (0.59) | ACEMMECPA1ACE2 | |
| SCHEMBL6468859 | 0.79 | ACE (0.59) | ACEMMECPA1ACE2 | |
| SCHEMBL21375005 | 0.79 | ACE (0.59) | ACEMMECPA1ACE2 | |
| SCHEMBL10555236 | 0.79 | MME (0.34) | ACEMMECPA1ACE2 | |
| SCHEMBL7362168 | 0.74 | MME (0.52) | ACEMMECPA1ACE2RAB9A | |
| SCHEMBL7725288 | 0.74 | MME (0.52) | ACEMMECPA1ACE2RAB9A | |
| SCHEMBL9652457 | 0.74 | MME (0.52) | ACEMMECPA1ACE2RAB9A | |
| SCHEMBL21030512 | 0.73 | MME (0.47) | ACEMMECPA1ACE2RAB9A | |
| SCHEMBL22342125 | 0.73 | MME (0.47) | ACEMMECPA1ACE2RAB9A | |
| SCHEMBL8927997 | 0.73 | MME (0.47) | ACEMMECPA1ACE2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082930-A | Diagnosis, tumors | MALLINCKRODT MEDICAL, INC. (US) | 1992-01-21 | — | — | US | disclosed |