Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | HTRA2 | O43464 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21356610 | 0.95 | ABCB1 (0.55) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL21375317 | 0.87 | ABCB1 (0.57) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL21375908 | 0.84 | ABCB1 (0.59) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL21375837 | 0.83 | ABCB1 (0.56) | ABCB1USP2CFTRPAX8ATM | |
| Trifluoroacetic Acid SCHEMBL21356618 | 0.82 | HDAC3 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| Trifluoroacetic Acid SCHEMBL21356615 | 0.82 | HDAC3 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| Trifluoroacetic Acid SCHEMBL21356611 | 0.82 | HDAC3 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| Trifluoroacetic Acid SCHEMBL21356616 | 0.82 | HDAC3 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| Trifluoroacetic Acid SCHEMBL21356619 | 0.82 | HDAC3 (0.53) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13662482 | 0.82 | ABCB1 (0.68) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10703737-B2 | HDAC inhibitors and uses thereof | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2020-07-07 | — | — | US | disclosed |
| US-20190284154-A1 | HDAC INHIBITORS AND USES THEREOF | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10703737-B2 | HDAC inhibitors and uses thereof | HDAC1, HDAC3, HDAC5 | ABCB1 4074/4885USP2 1516/4885CFTR 4286/4885 |
| US-20190284154-A1 | HDAC INHIBITORS AND USES THEREOF | HDAC1, HDAC3, HDAC5 | ABCB1 4074/4885USP2 1516/4885CFTR 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.