Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | USP2 | O75604 | 4/20 | 0.66 |
| ▸ | ATM | Q13315 | 2/20 | 0.66 |
| ▸ | CFTR | P13569 | 1/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.66 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GJA1 | P17302 | 1/20 | 0.36 |
| ▸ | GJB2 | P29033 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 4/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PLEC | Q15149 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399387 | 0.85 | ABCB1 (0.78) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL13662481 | 0.83 | ABCB1 (0.74) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL458205 | 0.83 | ABCB1 (0.77) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14176749 | 0.83 | ABCB1 (0.77) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL21375836 | 0.82 | ABCB1 (0.60) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL23309754 | 0.82 | ABCB1 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL9979456 | 0.82 | ABCB1 (0.79) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL5606345 | 0.82 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| Hydrochloric Acid SCHEMBL29376502 | 0.82 | USP2 (0.76) | ABCB1USP2ATMCFTRPAX8 | |
| SCHEMBL14693687 | 0.82 | ABCB1 (0.76) | ABCB1USP2ATMCFTRPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090257953-A1 | NOVEL FLUORINE-18 LABELED RHODAMINE DERIVATIVES FOR MYOCARDIAL PERFUSION IMAGING WITH POSITRON EMISSION TOMOGRAPHY | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090257953-A1 | NOVEL FLUORINE-18 LABELED RHODAMINE DERIVATIVES FOR MYOCARDIAL PERFUSION IMAGING WITH POSITRON EMISSION TOMOGRAPHY | FABP3, MPI, TNNI3 | ABCB1 403/4885USP2 3943/4885ATM 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.