Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 3/20 | 0.42 |
| ▸ | KDM4B | O94953 | 3/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665201 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL29978071 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL29978560 | 0.70 | ADORA3 (0.75) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL664225 | 0.70 | ADORA3 (0.75) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL664484 | 0.69 | ADORA3 (0.66) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL29978117 | 0.69 | ADORA3 (0.66) | SMN1; SMN2MAPK1LMNATDP1L3MBTL1 | |
| SCHEMBL663246 | 0.68 | MEN1 (0.71) | SMN1; SMN2MAPK1HPGDLMNATDP1 | |
| SCHEMBL21376512 | 0.67 | ADORA3 (0.66) | SMN1; SMN2MAPK1L3MBTL1MEN1RAB9A | |
| SCHEMBL29978012 | 0.67 | GRM1 (0.73) | SMN1; SMN2MAPK1HPGDLMNATDP1 | |
| SCHEMBL662995 | 0.67 | GRM1 (0.73) | SMN1; SMN2MAPK1HPGDLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |