Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376799 | 0.95 | SCD (0.60) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21376521 | 0.92 | SCD (0.62) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21909808 | 0.89 | MAPT (0.58) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21909805 | 0.82 | SCD (0.60) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL665605 | 0.81 | MAPT (0.79) | SCDKMT2AMEN1MAPTLMNA | |
| SCHEMBL21376803 | 0.81 | RXFP1 (0.56) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL663484 | 0.78 | MAPT (0.71) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL31065 | 0.78 | SCD (1.00) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL664543 | 0.78 | MAPT (0.80) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL21376338 | 0.78 | SCD (0.61) | SCDKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |