Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SCD | O00767 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376523 | 0.89 | SCD (0.62) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376532 | 0.86 | MAPT (0.70) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376799 | 0.84 | SCD (0.60) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL663583 | 0.80 | MAPT (0.82) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376521 | 0.80 | SCD (0.62) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5713530 | 0.76 | MAP3K5 (0.75) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376581 | 0.75 | ADORA3 (0.57) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21376928 | 0.75 | L3MBTL1 (0.61) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL29978060 | 0.73 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL662501 | 0.73 | MAPT (1.00) | MAPTKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |