Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26152399 | 0.87 | KDM4E (0.48) | HINT1NT5ETAAR1KRAS | |
| SCHEMBL1919142 | 0.85 | HINT1 (0.59) | HINT1PNPNT5EFUT5GSK3A | |
| SCHEMBL17597173 | 0.84 | POLB (0.56) | HINT1PNPNT5EPOLBFUT5 | |
| SCHEMBL6243042 | 0.79 | HINT1 (0.50) | HINT1PNPNT5ETAAR1FUT5 | |
| SCHEMBL3278946 | 0.79 | KDM4E (0.48) | HINT1STING1POLBFUT5HPGD | |
| SCHEMBL14896399 | 0.79 | HINT1 (0.49) | HINT1PNPNT5ETAAR1HPGD | |
| SCHEMBL6242507 | 0.78 | HINT1 (0.50) | HINT1PNPNT5ETAAR1FUT5 | |
| SCHEMBL20833132 | 0.77 | KDM4E (0.48) | HINT1STING1TAAR1FUT5KRAS | |
| SCHEMBL20833440 | 0.77 | KDM4E (0.49) | HINT1TAAR1 | |
| SCHEMBL6242581 | 0.76 | HINT1 (0.48) | HINT1PNPNT5ETAAR1FUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175260-A2 | MODIFIED OLIGONUCLEOTIDES AND METHODS OF USE IN TAUOPATHIES | JANSSEN PHARMACEUTICA NV (BE) | 2019-09-19 | — | — | WO | disclosed |