Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663005 | 0.82 | MAPT (0.60) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL21376926 | 0.82 | SCD (0.74) | SCDKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL21910767 | 0.81 | SCD (0.58) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL21376791 | 0.79 | SCD (0.64) | SCDKDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL21376599 | 0.79 | SCD (0.64) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL15478801 | 0.77 | SCD (0.62) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL16562088 | 0.75 | SCD (1.00) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL13941605 | 0.71 | SCD (0.55) | SCDHTTKDM4EL3MBTL1MEN1 | |
| SCHEMBL4912951 | 0.70 | SCD (1.00) | SCDMEN1KMT2AMAPTNPC1 | |
| SCHEMBL13941416 | 0.70 | KDM4E (0.53) | SCDHTTKDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |