Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478801 | 0.88 | SCD (0.62) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL2686124 | 0.84 | KDM4E (0.75) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14807738 | 0.84 | SCD (0.74) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4913650 | 0.84 | SCD (0.88) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13329390 | 0.83 | MAP3K5 (0.83) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14807016 | 0.82 | SCD (0.77) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL2483241 | 0.81 | SCD (0.84) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13941605 | 0.81 | SCD (0.55) | SCDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4378894 | 0.80 | MET (0.68) | SCDKMT2AMEN1NPC1RAB9A | |
| Bromide SCHEMBL2482639 | 0.80 | SCD (0.76) | SCDKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626240-A1 | PROCESS OF PREPARATION OF A N-ARYL BENZYL SULFONAMIDE SUBSTITUTED WITH AN AMIDO GROUP | StemSynergy Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-2403499-B1 | METHODS AND COMPOSITIONS FOR USE IN TREATING CANCER AND REDUCING WNT MEDIATED EFFECTS IN A CELL | STEMSYNERGY THERAPEUTICS INC (US) | 2019-09-18 | — | — | EP | disclosed |