Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 7/20 | 0.33 |
| ▸ | PGR | P06401 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376888 | 0.97 | HTT (0.38) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21377087 | 0.97 | HTT (0.38) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL12776556 | 0.92 | HTT (0.39) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21376885 | 0.92 | HTT (0.39) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21376889 | 0.84 | MAPT (0.32) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21377082 | 0.84 | MAPT (0.32) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL12793261 | 0.84 | HTT (0.43) | HTTLMNAMAPTKMT2AMEN1 | |
| SCHEMBL21377081 | 0.83 | LMNA (0.31) | HTTLMNA | |
| SCHEMBL21376881 | 0.83 | LMNA (0.31) | HTTLMNA | |
| SCHEMBL21376896 | 0.83 | HTT (0.35) | HTTLMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019174650-A1 | COMPOUND HAVING BENZENE CORE, PREPARATION METHOD THEREFOR AND USES THEREOF ON ORGANIC ELECTROLUMINESCENT DEVICE | 江苏三月光电科技有限公司 | 2019-09-19 | — | — | WO | disclosed |