Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18078117 | 1.00 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL22677474 | 1.00 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL19872227 | 1.00 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL24058545 | 0.97 | MME (0.43) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL22677413 | 0.95 | MME (0.45) | MMEMMEL1ACE | |
| SCHEMBL22677412 | 0.95 | MME (0.45) | MMEMMEL1ACE | |
| SCHEMBL22677493 | 0.93 | MME (0.49) | MMEMMEL1ACE | |
| SCHEMBL18078113 | 0.93 | MME (0.49) | MMEMMEL1ACE | |
| SCHEMBL24595272 | 0.93 | MME (0.49) | MMEMMEL1ACE | |
| SCHEMBL19872246 | 0.93 | MME (0.49) | MMEMMEL1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019175799-A2 | METHOD OF MODULATING TIGIT AND PD-1 SIGNALLING PATHWAYS USING 1,2,4-OXADIAZOLE COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2019-09-19 | — | — | WO | disclosed |