Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872227 | 0.97 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL22677474 | 0.97 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL21377698 | 0.97 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL18078117 | 0.97 | MME (0.45) | MMEMMEL1ACESLC6A2 | |
| SCHEMBL22677413 | 0.92 | MME (0.45) | MMEMMEL1ACE | |
| SCHEMBL22677412 | 0.92 | MME (0.45) | MMEMMEL1ACE | |
| SCHEMBL22677493 | 0.91 | MME (0.49) | MMEMMEL1ACELTA4H | |
| SCHEMBL19872246 | 0.91 | MME (0.49) | MMEMMEL1ACELTA4H | |
| SCHEMBL24595272 | 0.91 | MME (0.49) | MMEMMEL1ACELTA4H | |
| SCHEMBL18078113 | 0.91 | MME (0.49) | MMEMMEL1ACELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023645-A1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | Aurigene Discovery Technologies Limited (IN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3267984-B1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-11-24 | — | — | EP | disclosed |