Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.79 |
| ▸ | TP53 | P04637 | 7/20 | 0.79 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472235 | 1.00 | MAPT (0.79) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL14472233 | 0.83 | TP53 (0.58) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL14472234 | 0.83 | TP53 (0.58) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL2819014 | 0.82 | MAPT (0.65) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL2819017 | 0.82 | MAPT (0.65) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL2141246 | 0.82 | MAPT (0.83) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL2141243 | 0.82 | MAPT (0.83) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL22196893 | 0.81 | KMT2A (0.67) | MAPTTP53ALDH1A1KMT2AMEN1 | |
| SCHEMBL17465996 | 0.81 | MAPT (0.66) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL2138863 | 0.81 | TP53 (0.76) | MAPTTP53THRBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242774-B2 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2018-09-26 | — | — | EP | claimed |
| US-9249237-B2 | Self-repairing composition, self-repairing materials, self-repairing methods and applications | CATALYSE (FR) | 2016-02-02 | — | — | US | claimed |
| EP-2242774-B1 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2013-01-09 | — | — | EP | claimed |
| US-20110057340-A1 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2011-03-10 | — | — | US | claimed |