Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.83 |
| ▸ | TP53 | P04637 | 7/20 | 0.83 |
| ▸ | THRB | P10828 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141246 | 1.00 | MAPT (0.83) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL14472291 | 0.87 | TP53 (0.76) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL2138863 | 0.87 | TP53 (0.76) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL17465996 | 0.83 | MAPT (0.66) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL14472235 | 0.82 | MAPT (0.79) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL2137995 | 0.82 | MAPT (0.79) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL2825398 | 0.81 | MAPT (0.73) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL2825397 | 0.81 | MAPT (0.73) | MAPTTP53THRBLMNANPC1 | |
| SCHEMBL2576359 | 0.79 | ALDH1A1 (0.71) | MAPTLMNANPC1RAB9APOLB | |
| SCHEMBL988798 | 0.79 | ALDH1A1 (0.71) | MAPTLMNANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242774-B2 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2018-09-26 | — | — | EP | claimed |
| EP-2242774-B1 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2013-01-09 | — | — | EP | claimed |
| US-9249237-B2 | Self-repairing composition, self-repairing materials, self-repairing methods and applications | CATALYSE (FR) | 2016-02-02 | — | — | US | disclosed |
| US-20110057340-A1 | SELF-REPAIRING COMPOSITION, SELF-REPAIRING MATERIALS, SELF-REPAIRING METHODS AND APPLICATIONS | CATALYSE (FR) | 2011-03-10 | — | — | US | disclosed |