Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 6/20 | 0.54 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 4/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.49 |
| ▸ | LCK | P06239 | 4/20 | 0.49 |
| ▸ | CSF1R | P07333 | 4/20 | 0.49 |
| ▸ | BCR | P11274 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | DDX3X | O00571 | 1/20 | 0.49 |
| ▸ | GAK | O14976 | 1/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400972 | 0.86 | NPC1 (0.79) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL22958866 | 0.81 | RAB9A (0.62) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL22529530 | 0.81 | KIT (0.68) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL14409556 | 0.80 | SMN1; SMN2 (0.67) | RAB9ANPC1ALDH1A1BTKHDAC6 | |
| SCHEMBL13747820 | 0.80 | SMN1; SMN2 (0.67) | RAB9ANPC1ALDH1A1BTKHDAC6 | |
| SCHEMBL15381992 | 0.79 | BTK (0.69) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL12345537 | 0.79 | NPC1 (0.62) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL21400969 | 0.78 | RAB9A (0.66) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL16755297 | 0.78 | KIT (0.70) | RAB9ANPC1ALDH1A1BTKKIT | |
| SCHEMBL24024030 | 0.77 | RAB9A (0.73) | RAB9ANPC1ALDH1A1BTKHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768682-A1 | NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE | Allcron Pharma Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019182944-A1 | NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE | ALLCRON PHARMA INC. (US) | 2019-09-26 | — | — | WO | disclosed |