SCHEMBL21383377

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21388971	0.87	HTR2A (0.38)	RAB9AMAPTKDM4ENPSR1MEN1
	SCHEMBL21389060	0.83	TDP1 (0.44)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21389059	0.81	MAPT (0.41)	NPC1RAB9AMAPTKDM4ETSHR
	SCHEMBL21388967	0.80	MAPT (0.47)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21388973	0.80	MAPT (0.47)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21388979	0.78	MAPT (0.46)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21388997	0.76	MAPT (0.47)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21388974	0.76	MAPT (0.47)	RAB9AMAPTKDM4ETSHRNPSR1
	SCHEMBL21389064	0.74	ESR1 (0.48)	MEN1KMT2ADHODHMAPK1
	SCHEMBL21388969	0.74	GAA (0.42)	ALDH1A1MAPK14GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.