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SCHEMBL21383940

SCHEMBL21383940

CC[C@H]1CC(=O)N(CCNC(=O)CSCC(=O)O)C1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ HDAC3 O15379 1/20 0.37
▸ HDAC4 P56524 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC7 Q8WUI4 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ HDAC10 Q969S8 1/20 0.37
▸ HDAC11 Q96DB2 1/20 0.37
▸ HDAC8 Q9BY41 1/20 0.37
▸ HDAC6 Q9UBN7 1/20 0.37
▸ HDAC9 Q9UKV0 1/20 0.37
▸ HDAC5 Q9UQL6 1/20 0.37
▸ USP2 O75604 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ FABP3 P05413 1/20 0.35
▸ FABP4 P15090 1/20 0.35
▸ GAA P10253 1/20 0.33
▸ FOLH1 Q04609 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389372 1.00 L3MBTL1 (0.38) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL24796626 1.00 L3MBTL1 (0.38) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL21389308 0.90 CYP2C19 (0.38) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL26746679 0.90 HDAC3 (0.37) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL26746672 0.90 HDAC3 (0.37) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL24796163 0.85 HPGD (0.41) L3MBTL1CYP2C19GAAKMT2AALDH1A1
SCHEMBL24796674 0.85 CYP1A2 (0.36) L3MBTL1CYP2C19HDAC3HDAC4HDAC1
SCHEMBL24795884 0.85 USP2 (0.37) L3MBTL1CYP2C19USP2TSHRFABP3
SCHEMBL21389230 0.85 USP2 (0.37) L3MBTL1CYP2C19USP2TSHRFABP3
SCHEMBL21383848 0.84 FABP3 (0.37) L3MBTL1USP2FABP3FABP4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed
EP-3768294-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS Carmot Therapeutics, Inc. (US) 2021-01-27 — — EP disclosed
CN-112236161-A Modulators of G protein-coupled receptors 卡莫特治疗学股份有限公司 2021-01-15 — — CN disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 — — WO disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR L3MBTL1 2127/4885CYP2C19 3819/4885HDAC3 776/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR L3MBTL1 2161/4885CYP2C19 3830/4885HDAC3 733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.