⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25188589 | 0.97 | — | — | |
| SCHEMBL25260331 | 0.76 | — | — | |
| SCHEMBL24847108 | 0.74 | DRD2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29896756 | 0.72 | DRD2 (0.32) | — | |
| SCHEMBL9396100 | 0.71 | — | — | |
| SCHEMBL29896722 | 0.70 | — | — | |
| SCHEMBL11361955 | 0.69 | — | — | |
| SCHEMBL24853961 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL31642342 | 0.67 | — | — | |
| SCHEMBL14964520 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398119-B2 | Piperazine azaspiro derivatives | PFIZER INC. (US) | 2025-08-26 | — | — | US | disclosed |
| EP-4219464-A1 | PIPERAZINE AZASPIRO DERIVAVES | Pfizer Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230192654-A1 | PIPERAZINE AZASPIRO DERIVATIVES | PFIZER INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | disclosed |
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | disclosed |
| EP-3768669-B1 | PIPERAZINE AZASPIRO DERIVAVES | PFIZER (US) | 2023-01-25 | — | — | EP | disclosed |
| US-11524954-B2 | Piperazine azaspiro derivatives | PFIZER INC. (US) | 2022-12-13 | — | — | US | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |
| US-20210024497-A1 | PIPERAZINE AZASPIRO DERIVAVES | PFIZER INC. | 2021-01-28 | — | — | US | disclosed |
| EP-3768669-A1 | PIPERAZINE AZASPIRO DERIVAVES | Pfizer Inc (US) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019183636-A1 | PIPERAZINE AZASPIRO DERIVAVES | PFIZER INC. (US) | 2019-09-26 | — | — | WO | disclosed |