Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | CCR3 | P51677 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 5/20 | 0.47 |
| ▸ | PREP | P48147 | 5/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826433 | 0.82 | CHRM2 (0.57) | CHRM2CCR3FAPPREPPDE2A | |
| SCHEMBL21384601 | 0.81 | IDO1 (0.54) | CHRM2CCR3 | |
| SCHEMBL21400794 | 0.81 | IDO1 (0.54) | CHRM2CCR3 | |
| SCHEMBL21400790 | 0.81 | IDO1 (0.54) | CHRM2CCR3 | |
| SCHEMBL21400645 | 0.79 | CCR3 (0.49) | CHRM2CCR3KMT2A | |
| SCHEMBL16002921 | 0.79 | CHRM2 (0.52) | CHRM2CCR3FAPPREPPDE2A | |
| SCHEMBL21381377 | 0.79 | CHRM2 (0.57) | CHRM2CCR3FAPPDE2AUSP2 | |
| SCHEMBL21400643 | 0.77 | CCR3 (0.50) | CHRM2CCR3 | |
| SCHEMBL31395273 | 0.77 | KMT2A (0.60) | CHRM2CCR3PDE2AUSP2DNMT1 | |
| SCHEMBL21385177 | 0.76 | GFER (0.48) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111630043-B | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-111630043-A | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |