SCHEMBL21400643 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CCR3	P51677	2/20	0.50

▸	IDO1	P14902	7/20	0.47

▸	CYP2C9	P11712	2/20	0.47

▸	CYP3A4	P08684	1/20	0.47

▸	CYP2C8	P10632	1/20	0.47

▸	TDO2	P48775	1/20	0.47

▸	KCNH2	Q12809	1/20	0.47

▸	CHRM2	P08172	2/20	0.45

▸	MGLL	Q99685	1/20	0.43

▸	UBE2M	P61081	1/20	0.41

▸	DCUN1D1	Q96GG9	1/20	0.41

▸	ACLY	P53396	1/20	0.40

▸	TRPV1	Q8NER1	1/20	0.40

▸	GFER	P55789	1/20	0.40

▸	SYK	P43405	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21400645	0.88	CCR3 (0.49)	CCR3IDO1CYP2C9CYP3A4CYP2C8
SCHEMBL21400790	0.88	IDO1 (0.54)	CCR3IDO1CYP2C9CYP3A4CYP2C8
SCHEMBL21384601	0.88	IDO1 (0.54)	CCR3IDO1CYP2C9CYP3A4CYP2C8
SCHEMBL21400794	0.88	IDO1 (0.54)	CCR3IDO1CYP2C9CYP3A4CYP2C8
SCHEMBL21400802	0.83	CCR3 (0.56)	CCR3IDO1CHRM2MGLL
SCHEMBL18806694	0.82	IDO1 (0.66)	IDO1CYP2C9CYP3A4CYP2C8TDO2
SCHEMBL18806696	0.82	IDO1 (0.66)	IDO1CYP2C9CYP3A4CYP2C8TDO2
SCHEMBL17762855	0.82	IDO1 (0.66)	IDO1CYP2C9CYP3A4CYP2C8TDO2
SCHEMBL18806697	0.82	IDO1 (0.66)	IDO1CYP2C9CYP3A4CYP2C8TDO2
SCHEMBL21400800	0.81	IDO1 (0.69)	IDO1CYP2C9CYP3A4CYP2C8TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019179369-A1	RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF	四川科伦博泰生物医药股份有限公司	2019-09-26	—	—	WO	disclosed