SCHEMBL21385196

SCHEMBL21385196

C=CC(=O)OC(C)SC(C)SCC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673221 0.88 TSHR (0.40) TSHRHPGD
SCHEMBL2425036 0.85 TSHR (0.44) TSHRHPGD
SCHEMBL7709947 0.85 TSHR (0.42) TSHRHPGD
SCHEMBL672391 0.81 TSHR (0.45) TSHRHPGD
SCHEMBL21624969 0.79 TSHR (0.41) TSHRHPGD
SCHEMBL2432049 0.77 TSHR (0.42) TSHRHPGD
SCHEMBL28107882 0.77 TSHR (0.42) TSHRHPGD
SCHEMBL21385093 0.76 TSHR (0.39) TSHR
SCHEMBL7563890 0.76 TSHR (0.45) TSHRHPGD
SCHEMBL10427181 0.76 TSHR (0.41) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768746-A Compound for optical material, curable composition, cured product, and optical article 株式会社德山 2023-03-07 CN disclosed
CN-115066472-A Primer composition for optical article and laminate 株式会社德山 2022-09-16 CN disclosed
CN-114846047-A Moisture-curable polyurethane composition and laminate 株式会社德山 2022-08-02 CN disclosed
CN-114829539-A Photochromic curable composition and photochromic optical article 株式会社德山 2022-07-29 CN disclosed
CN-110799573-B Photochromic polyrotaxane compound, and curable composition comprising same 株式会社德山 2022-06-03 CN disclosed
CN-113166310-B Curable composition for optical material and optical material 株式会社德山 2022-05-31 CN disclosed
CN-114051497-A Chromene compound and photochromic optical article 株式会社德山 2022-02-15 CN disclosed
WO-2021241596-A1 COMPOUND FOR OPTICAL MATERIAL, CURABLE COMPOSITION, CURED BODY, AND OPTICAL ARTICLE 株式会社トクヤマ 2021-12-02 WO disclosed
CN-109563219-B Photochromic curable composition, use thereof, and polyrotaxane monomer 株式会社德山 2021-11-19 CN disclosed
CN-113227158-A Curable composition for optical material and optical material 株式会社德山 2021-08-06 CN disclosed
CN-113166310-A Curable composition for optical material and optical material 株式会社德山 2021-07-23 CN disclosed
CN-112424260-A Photochromic compound and curable composition containing same 株式会社德山 2021-02-26 CN disclosed
CN-112105676-A Low water content polyrotaxane monomer and curable composition containing the same 株式会社德山 2020-12-18 CN disclosed
CN-111936524-A Photochromic curable composition 株式会社德山 2020-11-13 CN disclosed
CN-110869355-A Benzopyran compound, curable composition containing benzopyran compound, and optical article containing cured product formed from curable composition 株式会社德山 2020-03-06 CN disclosed
CN-110799573-A Photochromic polyrotaxane compound, and curable composition comprising same 株式会社德山 2020-02-14 CN disclosed
WO-2020017610-A1 PHOTOCHROMIC COMPOUND AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC COMPOUND 株式会社トクヤマ 2020-01-23 WO disclosed
WO-2019182085-A1 PHOTOCHROMIC CURABLE COMPOSITION 株式会社トクヤマ 2019-09-26 WO disclosed