Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672391 | 0.91 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7709947 | 0.87 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL4307337 | 0.84 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29134968 | 0.83 | TSHR (0.39) | TSHRHPGD | |
| SCHEMBL21624969 | 0.80 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2435317 | 0.80 | — | — | |
| SCHEMBL673221 | 0.79 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28029833 | 0.78 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL21385196 | 0.77 | TSHR (0.39) | TSHRHPGD | |
| SCHEMBL7563890 | 0.77 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776399-B1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIV GENT (BE) | 2012-11-14 | — | — | EP | claimed |
| EP-3018151-A1 | PROCESS FOR PREPARING INERT RAFT POLYMERS | Universiteit Gent (BE) | 2016-05-11 | — | — | EP | disclosed |
| US-20130096268-A1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIVERSITEIT GENT (BE) | 2013-04-18 | — | — | US | disclosed |
| US-20130046087-A1 | Substituted Cyclodextrin Derivatives Useful As Intermediates For Producing Biologically Active Materials | ARCARIOS BV (NL) | 2013-02-21 | — | — | US | disclosed |
| EP-2550299-A2 | Substituted cyclodextrin derivatives and process for their preparation | Arcarios B.V. (NL) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011117317-A2 | SUBSTITUTED CYCLODEXTRIN DERIVATIVES USEFUL AS INTERMEDIATES FOR PRODUCING BIOLOGICALLY ACTIVE MATERIALS | ARCARIOS BV (NL) | 2011-09-29 | — | — | WO | disclosed |
| US-20080262160-A1 | Monodisperse Polymers Containing (Alkyl)Acrylic Acid Moieties, Precursors and Methods for Making them and their Applications | UNIVERSITEIT GENT (BE) | 2008-10-23 | — | — | US | disclosed |
| EP-1776399-A1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIVERSITEIT GENT (BE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006002496-A1 | MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS | UNIVERSITEIT GENT (BE) | 2006-01-12 | — | — | WO | disclosed |