⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30999153 | 1.00 | — | — | |
| SCHEMBL29333213 | 0.82 | GBA1 (0.39) | — | |
| SCHEMBL6377016 | 0.82 | GBA1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL6371151 | 0.79 | GBA1 (0.37) | — | |
| SCHEMBL29297432 | 0.77 | CPN1 (0.36) | — | |
| SCHEMBL24558960 | 0.76 | — | — | |
| SCHEMBL12524842 | 0.76 | — | — | |
| SCHEMBL446995 | 0.76 | — | — | |
| SCHEMBL18631320 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL322359 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421724-B2 | Compositions for preventing and/or treating degenerative disorders of the central nervous system | AMICUS THERAPEUTICS, INC. (US) | 2019-09-24 | — | — | US | disclosed |