SCHEMBL2138575

SCHEMBL2138575

O=C(O)OC(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.43
KCNN4 O15554 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1A2 P05177 3/20 0.43
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
CES1 P23141 1/20 0.39
CYP2C9 P11712 2/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9806676 0.86 CYP2C19 (0.43) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL14878271 0.82 KCNN4 (0.45) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL10879317 0.82 MAPT (0.47) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL9125726 0.82 CYP2C19 (0.41) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL4504520 0.79 KCNN4 (0.42) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL2442870 0.78 KCNN4 (0.45) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL28769396 0.76 KCNN4 (0.43) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL11244960 0.76 CYP2C19 (0.54) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL2345811 0.74 CYP1A2 (0.52) CYP2C19KCNN4HIF1ACYP1A2CYP2D6
SCHEMBL6552317 0.74 ALDH1A1 (0.58) CYP2C19KCNN4HIF1ACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554277-B1 RESIN-COATED AL PLATE FOR DRAWN AND IRONED CAN WITH EXCELLENT LUSTER AND METHOD FOR PRODUCING DRAWN AND IRONED CAN TOYO KOHAN CO LTD (JP) 2019-06-19 EP disclosed
US-10086586-B2 Composite Al material for drawn and ironed can TOYO KOHAN CO., LTD. (JP) 2018-10-02 US disclosed
US-9662699-B2 Resin-coated A1 plate for drawn and ironed can with excellent luster and method for producing drawn and ironed can TOYO KOHAN CO., LTD. (JP) 2017-05-30 US disclosed
EP-2444245-B1 COMPOSITE Al MATERIAL FOR DRAWN AND IRONED CAN TOYO KOHAN CO LTD (JP) 2015-12-16 EP disclosed
US-20130164497-A1 Resin-Coated Al Plate for Drawn and Ironed Can with Excellent Luster and Method for Producing Drawn and Ironed Can TOYO KOHAN CO., LTD. (JP) 2013-06-27 US disclosed
EP-2554277-A1 RESIN-COATED Al PLATE FOR DRAWN AND IRONED CAN WITH EXCELLENT LUSTER AND METHOD FOR PRODUCING DRAWN AND IRONED CAN Toyo Kohan Co., Ltd. (JP) 2013-02-06 EP disclosed
US-20120164440-A1 COMPOSITE AL MATERIAL FOR DRAWN AND IRONED CAN TOYO KOHAN CO., LTD. (JP) 2012-06-28 US disclosed
EP-2444245-A1 COMPOSITE Al MATERIAL FOR DRAWN AND IRONED CAN Toyo Kohan Co., Ltd. (JP) 2012-04-25 EP disclosed
EP-0209393-B1 DEEP-DRAW-FORMED VESSEL AND PROCESS FOR PREPARATION THEREOF TOYO SEIKAN KAISHA LIMITED (JP) 1991-05-02 EP disclosed
EP-0118226-B2 VESSEL CONTAINING A PLASTIC LAMINATE STRUCTURE TOYO SEIKAN KAISHA LIMITED (JP) 1990-10-10 EP disclosed
EP-0078625-A1 Easily-openable heat seal lid TOYO SEIKAN KAISHA LIMITED (JP) 1983-05-11 EP disclosed
US-4382525-A THERMOSETTING AND THERMOPLASTIC RESINS TOYO SEIKAN KAISHA, LTD. (JP) 1983-05-10 US disclosed
EP-0076634-A1 Process for preparation of metallic bottles TOYO SEIKAN KAISHA LIMITED (JP) 1983-04-13 EP disclosed
EP-0075427-A2 Metal vessel having circumferential side seam and process for production thereof TOYO SEIKAN KAISHA LIMITED (JP) 1983-03-30 EP disclosed
EP-0065417-A2 Easily-openable heat seal lid TOYO SEIKAN KAISHA LIMITED (JP) 1982-11-24 EP disclosed
US-4255490-A COPOLYMERS ACETALIZED WITH A MONO- OR DIALDEHYDE; FOOD PACKAGING FILMS, HEAT AND SOLVENT RESISTANCE; OXYGEN BARRIER TOYO SEIKAN KAISHA LIMITED (JP) 1981-03-10 US disclosed
US-4212956-A PACKAGING FILM TOYO SEIKAN KAISHA LIMITED (JP) 1980-07-15 US disclosed
US-3975463-A Molded structures containing crystalling polyolefin saponified ethylene vinyl acetate copolymer and carbonyl containing copolymers TOYO SEIKAN KAISHA LIMITED (JA) 1976-08-17 US disclosed
US-3932692-A Resinious laminates having improved gas permeation and delamination resistance TOYO SEIKAN KAISHA LIMITED (JA) 1976-01-13 US disclosed
US-3931449-A Resinous laminates having improved gas permeation and resistance to delamination TOYO SEIKAN KAISHA LIMITED (JA) 1976-01-06 US disclosed