Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21898154 | 0.87 | MAPT (0.38) | NR3C1PGRARMAPTALDH1A1 | |
| SCHEMBL16577662 | 0.86 | MAPT (0.39) | MAPTALDH1A1HPGDNPSR1CRHBP | |
| SCHEMBL24004252 | 0.86 | MAPT (0.39) | MAPTALDH1A1HPGDNPSR1CRHBP | |
| SCHEMBL22648603 | 0.85 | CD274 (0.44) | MAPTNPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL16577664 | 0.82 | NR3C2 (0.40) | MAPTALDH1A1HPGDNPSR1CRHBP | |
| SCHEMBL6125416 | 0.82 | MEN1 (0.42) | ALDH1A1HPGDSLC6A9MEN1KMT2A | |
| SCHEMBL16559084 | 0.81 | PGR (0.49) | NR3C1PGRARMAPTALDH1A1 | |
| SCHEMBL22435770 | 0.80 | MAPT (0.41) | MAPTALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL24910157 | 0.80 | MAPT (0.41) | MAPTALDH1A1HPGDNPSR1MEN1 | |
| SCHEMBL22435842 | 0.80 | MAPT (0.41) | MAPTALDH1A1HPGDNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305764-B1 | DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-09-25 | — | — | EP | disclosed |