Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | BLK | P51451 | 1/20 | 0.55 |
| ▸ | JAK3 | P52333 | 4/20 | 0.48 |
| ▸ | HCK | P08631 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386655 | 0.96 | BTK (0.60) | BTKEGFRBLKHCK | |
| SCHEMBL21386788 | 0.93 | BTK (0.59) | BTKEGFRBLKJAK3JAK1 | |
| SCHEMBL21386703 | 0.92 | BTK (0.58) | BTKEGFRBLKJAK3JAK1 | |
| SCHEMBL21386776 | 0.91 | BTK (0.57) | BTKEGFRBLKJAK3JAK1 | |
| SCHEMBL21386725 | 0.91 | BTK (0.67) | BTKEGFRBLKJAK3HCK | |
| SCHEMBL21386763 | 0.89 | BTK (0.58) | BTKEGFRBLKJAK3JAK1 | |
| SCHEMBL21386752 | 0.88 | BTK (0.53) | BTKEGFRBLK | |
| SCHEMBL21386778 | 0.88 | BTK (0.66) | BTKEGFRBLKJAK3JAK1 | |
| SCHEMBL21386773 | 0.88 | BTK (0.52) | BTKEGFRBLKJAK3 | |
| SCHEMBL21386772 | 0.87 | BTK (0.51) | BTKEGFRBLKJAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543239-A1 | SELECTIVE BRUTON'S TYROSINE KINASE INHIBITOR AND USE THEREOF | Hangzhou Hertz Pharmaceutical Co., Ltd. (CN) | 2019-09-25 | — | — | EP | disclosed |