Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.77 |
| ▸ | SHBG | P04278 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.77 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Progesterone SCHEMBL20409003 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL20342397 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL17750737 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL3932110 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL12090497 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL23568915 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL13259536 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL7671 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL15224316 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA | |
| Progesterone SCHEMBL8430168 | 0.87 | CYP3A4 (1.00) | ALDH1A1CYP3A4SMN1; SMN2SERPINA6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542786-A1 | PROGESTERONE INTRAVAGINAL DEVICES | ITF Research Pharma, S.L.U. (ES) | 2019-09-25 | — | — | EP | disclosed |