⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368994 | 0.81 | — | — | |
| SCHEMBL302926 | 0.81 | — | — | |
| SCHEMBL154139 | 0.81 | — | — | |
| SCHEMBL29691639 | 0.79 | CYP11B1 (0.86) | — | |
| SCHEMBL29691623 | 0.79 | CYP11B1 (0.86) | — | |
| SCHEMBL8911420 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL73921 | 0.77 | — | — | |
| SCHEMBL29691464 | 0.77 | CYP11B1 (0.82) | — | |
| SCHEMBL29691514 | 0.77 | CYP11B1 (0.82) | — | |
| SCHEMBL29691532 | 0.77 | CYP11B1 (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853729-B | Quinazoline-2-ketone compound and preparation method and application thereof | 汕头大学医学院 | 2024-03-29 | — | — | CN | claimed |
| CN-115785091-A | Method for catalytically synthesizing tetrahydro-beta-carboline compound by utilizing PNP type pincerlike manganese catalyst | 邵秀兰 | 2023-03-14 | — | — | CN | claimed |
| CN-114853729-A | Quinazoline-2-ketone compound and preparation method and application thereof | 汕头大学医学院 | 2022-08-05 | — | — | CN | claimed |
| CN-110511214-B | Diamine substituted aromatic heterocyclic compound and preparation method and application thereof | 浙江工业大学 | 2021-07-27 | — | — | CN | claimed |
| EP-3226868-A1 | NOVEL QUINAZOLINES AS BIOGENIC AMINE TRANSPORT MODULATORS | Ananthan, Subramaniam (US) | 2017-10-11 | — | — | EP | claimed |
| EP-3226867-A1 | HETEROCYCLIC COMPOUNDS AS BIOGENIC AMINE TRANSPORT MODULATORS | Ananthan, Subramaniam (US) | 2017-10-11 | — | — | EP | claimed |
| US-9745305-B2 | Modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2017-08-29 | — | — | US | claimed |
| CN-107080700-A | Include the colouring compositions of fatty material, Pyrazolopyridine oxidation base and colour coupler | 莱雅公司 | 2017-08-22 | — | — | CN | claimed |
| EP-2970305-B1 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2017-02-22 | — | — | EP | claimed |
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | claimed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | claimed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | claimed |
| EP-0673254-A1 | 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1995009859-A1 | BOROPEPTIDE INHIBITORS OF THROMBIN WHICH CONTAIN A SUBSTITUTED PYRROLIDINE RING | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-13 | — | — | WO | claimed |
| WO-1994019008-A1 | COMBINATIONS OF RETROVIRAL INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-01 | — | — | WO | claimed |
| WO-1994013313-A1 | 6-POSITION MODIFIED DECAPEPTIDE LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 1994-06-23 | — | — | WO | claimed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | claimed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | claimed |
| EP-0289639-A1 | Use of trigonellin to revive, to stimulate and to enhance hair growth | Mai, Jutta (DE) | 1988-11-09 | — | — | EP | claimed |