Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 4/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387551 | 1.00 | ZDHHC20 (0.45) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL11585047 | 0.98 | ZDHHC20 (0.42) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL20274383 | 0.80 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL20267844 | 0.80 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL18431521 | 0.80 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL20274373 | 0.80 | ZDHHC20 (0.64) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL611182 | 0.80 | CA12 (0.41) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL8393428 | 0.78 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL8393427 | 0.78 | CA12 (0.50) | ZDHHC20ZDHHC2CA12CA1CA9 | |
| SCHEMBL1076719 | 0.78 | ZDHHC20 (0.61) | ZDHHC20ZDHHC2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542779-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2019-09-25 | — | — | EP | disclosed |