SCHEMBL21389084

SCHEMBL21389084

CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(C)C)C(=O)C(C)C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NOD1 Q9Y239 10/20 0.62
▸ GLP1R P43220 8/20 0.58
▸ EPHX2 P34913 1/20 0.53
▸ SLC6A5 Q9Y345 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24494715 0.97 NOD1 (0.60) NOD1GLP1REPHX2SLC6A5
SCHEMBL26743907 0.93 NOD1 (0.67) NOD1GLP1REPHX2SLC6A5
SCHEMBL21389083 0.93 NOD1 (0.53) NOD1GLP1REPHX2SLC6A5
SCHEMBL21389120 0.92 NOD1 (0.63) NOD1GLP1REPHX2SLC6A5
SCHEMBL25715324 0.92 NOD1 (0.59) NOD1GLP1REPHX2SLC6A5
SCHEMBL21389122 0.91 NOD1 (0.62) NOD1GLP1REPHX2SLC6A5
SCHEMBL25715319 0.90 NOD1 (0.63) NOD1GLP1REPHX2SLC6A5
SCHEMBL21686255 0.90 NOD1 (0.63) NOD1GLP1REPHX2SLC6A5
SCHEMBL24796367 0.89 NOD1 (0.62) NOD1GLP1REPHX2SLC6A5
SCHEMBL21389085 0.89 GLP1R (0.50) NOD1GLP1REPHX2SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20220177537-A1 LONG-ACTING OXYNTOMODULIN HYBRID PEPTIDE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF CHINA PHARMACEUTICAL UNIVERSITY (CN) 2022-06-09 — — US disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR NOD1 1118/4885GLP1R 2/4885EPHX2 2665/4885
US-20220177537-A1 LONG-ACTING OXYNTOMODULIN HYBRID PEPTIDE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF DPP4, GLP1R, VIP NOD1 1661/4885GLP1R 2/4885EPHX2 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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