Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26745878 | 1.00 | USP2 (0.40) | USP2PTGER4ALDH1A1CHRM2CHRM4 | |
| SCHEMBL21389216 | 1.00 | USP2 (0.40) | USP2PTGER4ALDH1A1CHRM2CHRM4 | |
| SCHEMBL26746723 | 0.90 | CHRM2 (0.35) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26746727 | 0.90 | CHRM2 (0.35) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21389200 | 0.86 | PTGER4 (0.36) | USP2PTGER4ALDH1A1GAAP2RX7 | |
| SCHEMBL24795987 | 0.85 | HPGD (0.43) | USP2ALDH1A1GAA | |
| SCHEMBL21389390 | 0.85 | CYP1A2 (0.38) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26745025 | 0.85 | PTGER4 (0.39) | USP2PTGER4GAAPER2P2RX7 | |
| SCHEMBL26744951 | 0.85 | PTGER4 (0.39) | USP2PTGER4GAAPER2P2RX7 | |
| SCHEMBL21384151 | 0.84 | PTGER4 (0.35) | USP2PTGER4ALDH1A1GAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |