Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389216 | 1.00 | USP2 (0.40) | USP2PTGER4ALDH1A1CHRM2CHRM4 | |
| SCHEMBL21389218 | 1.00 | USP2 (0.40) | USP2PTGER4ALDH1A1CHRM2CHRM4 | |
| SCHEMBL26746723 | 0.90 | CHRM2 (0.35) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26746727 | 0.90 | CHRM2 (0.35) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21389200 | 0.86 | PTGER4 (0.36) | USP2PTGER4ALDH1A1GAAP2RX7 | |
| SCHEMBL24795987 | 0.85 | HPGD (0.43) | USP2ALDH1A1GAA | |
| SCHEMBL21389390 | 0.85 | CYP1A2 (0.38) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26745025 | 0.85 | PTGER4 (0.39) | USP2PTGER4GAAPER2P2RX7 | |
| SCHEMBL26744951 | 0.85 | PTGER4 (0.39) | USP2PTGER4GAAPER2P2RX7 | |
| SCHEMBL21384151 | 0.84 | PTGER4 (0.35) | USP2PTGER4ALDH1A1GAAP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | USP2 2595/4885PTGER4 880/4885ALDH1A1 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.