Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24796402 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP3A4KMT2AALDH1A1KDM4E | |
| SCHEMBL24796658 | 0.86 | CYP1A2 (0.38) | CYP1A2CYP3A4KMT2AALDH1A1KDM4E | |
| SCHEMBL26746510 | 0.85 | HPGD (0.32) | KMT2AHPGDALDH1A1POLBL3MBTL1 | |
| SCHEMBL24796018 | 0.85 | MAPT (0.33) | KMT2AHPGDALDH1A1POLBL3MBTL1 | |
| SCHEMBL21389301 | 0.85 | FABP3 (0.34) | KMT2AHPGDALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL26634663 | 0.85 | FABP3 (0.34) | KMT2AHPGDALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL21383821 | 0.85 | FABP3 (0.34) | KMT2AHPGDALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL26746501 | 0.85 | HPGD (0.32) | KMT2AHPGDALDH1A1POLBL3MBTL1 | |
| SCHEMBL24796413 | 0.85 | HPGD (0.40) | KMT2AMEN1HPGDALDH1A1KDM4E | |
| SCHEMBL24796027 | 0.84 | CYP1A2 (0.36) | CYP1A2CYP3A4KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |