Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26746510 | 1.00 | HPGD (0.32) | HPGDHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL21383821 | 0.91 | FABP3 (0.34) | HPGDHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL21389301 | 0.91 | FABP3 (0.34) | HPGDHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL24796018 | 0.91 | MAPT (0.33) | HPGDHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL26634663 | 0.91 | FABP3 (0.34) | HPGDHTTSMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL21389368 | 0.85 | CYP1A2 (0.36) | HPGDSMN1; SMN2ALDH1A1NPSR1KMT2A | |
| SCHEMBL24796413 | 0.85 | HPGD (0.40) | HPGDSMN1; SMN2ALDH1A1NPSR1KMT2A | |
| SCHEMBL26746253 | 0.84 | KDM4E (0.33) | HTTALDH1A1FOLH1KMT2AHDAC3 | |
| SCHEMBL26746697 | 0.84 | KMT2A (0.32) | HTTSMN1; SMN2ALDH1A1FOLH1KMT2A | |
| SCHEMBL26746691 | 0.84 | KMT2A (0.32) | HTTSMN1; SMN2ALDH1A1FOLH1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | HPGD 2145/4885HTT 722/4885SMN1; SMN2 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.